DNA-stabilized silver nanoclusters (DNA:AgNCs) are a new and intriguing class of fluorophores that contain a limited number of silver atoms (usually < 30) wrapped in one or several single stranded DNA oligomers. These emitters have been finding uses for diverse applications spanning from sensing to fluorescence imaging. The color, brightness and photostability of AgNCs formed in the DNA scaffold are difficult to predict based on the DNA sequence, although significant advances have been made using machine learning tools. In addition, atomic structures of AgNCs and their interactions with the DNA scaffold have started to appear recently in the literature. Here you can see the crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (PDB code: 6M2P)

#molecularart ... #immolecular ... #nanocluster ... #silver ... #dna ... #complex ... #fluorescence ... #xray

Structure rendered with @proteinimaging and depicted with @corelphotopaint

Silver-DNA complex
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Silver-DNA complex

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